The Effect of Channa striata Extract on Serum Albumin and High Sensitive C-Reactive Protein in End-Stage Renal Disease Patients: A Randomized Controlled Trial

Background: Albumin is a marker of nutritioinal inflammation and mortality. Chronic inflammation, as indicated by the concentration proinflammatory cytokine, high sensitivity C-reactive protein (hs-CRP) was reported to be in end-stage renal disease (ESRD) patients. Channa striata (CS) contains that can increase albumin levels has anti-inflammatory effects. This study conducted determine effect CS extract on serum hs-CRP ESRD Methods: randomized, double blind, placebo-controlled patients with hemodialysis (HD) continuous ambulatory peritoneal dialysis (CAPD). Subjects were randomized either or placebo group given three times daily dosage 500 mg maltodextrin, respectively for 21 days. Serum measured at baseline, end study. Result: Forty subjects into 20 group, HD CAPD patient evenly distributed among group. Significant (p<0,001) significant decrease observed treatment compared control At study, there no difference between albumin, hs-CRP, their gradient intervention Conclusion: results higher lower our population.